Research Progress in Area 2 方向 ( 二 ) 課題進展 125 Abstract Endocrine disrupting chemicals (EDCs), even when occurring in very low concentrations (ppt) in the environment, can disturb hormonal balance, leading to reproductive impairment, abnormal development, growth retardation, cancers and diseases in animals. Due to their huge production, extensive use and low removal efficiencies from sewage, many EDCs are now found in high concentrations in sewage and our marine environment, especially in Hong Kong and the Pearl River Delta (PRD). Using the molecular imprinting technique, Prof. Lam proposes to develop novel technologies for in situ detection and field monitoring of EDCs in marine water and wastewater. This pioneer research attempts to address the detection and monitoring problem presented by this class of important pollutants of global concern. The molecularly imprinted polymer-based (MIP-based) sensors for in situ monitoring developed in this study is likely to be adopted by regulatory authorities for practical and routine uses, and may also have a very good potential for commercialization. Research Activities and Progress • Started the fabrication work on molecularly imprinted polymers for the recognition and binding of triphenyltin chloride. • Fabricated the first batch of polymer. • Synthesized triphenylmethyl ammonium iodide as the molecular template. Key Findings • Silica-based materials show outstanding performance in the molecular imprinting and specific binding of triphenyltin and monobutyltin. • The first batch of molecularly imprinted polymer for triphenyltin and monobutyltin compounds has already been successfully fabricated. • Evaluation of the molecularly imprinted polymer is underway. Research Output Publication 0 Trained personnel 2 Development of "Electronic Tongues" for in situ Monitoring of Endocrine Disrupting Chemicals in the Marine Environment Prof. Michael Hon-Wah Lam City University of Hong Kong Fig 1. Response curve for molecule MPABA.
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