46 The Hong Kong Branch researcher team led by Prof. WenXiong Wang developed a novel biosensor for labile Zn (II) quantification. The principle is based on the Zn2+-induced significant enhancement of autofluorescence intensity of an adenine deficient yeast (Ade(− ) yeast). The biosensor displays high tolerance to salinity, pH variation and other metals, and could detect Zn2+ with a lower quantification limit (0.01 μM) than the chemosensor and higher simplicity than the conventional method (ICP-MS coupled with ultrafiltration). It is possible to be used to detect labile Zn(II) species at trace levels in complex media. The research findings have been published on an international journal Biosensors and Bioelectronics. Reference: Biosensors and Bioelectronics 2021, 179, 1-8 香港分部王文雄教授研究团队开发一种新 型生物传感器，用于定量测定环境中不稳 定锌 ( I I )。该传感器的检测原理是依靠锌 ( I I )诱导提高缺乏腺嘌呤酵母的自发荧光 强度。该生物传感器对盐度、pH值变化 和其他金属具有较高的耐受性。与传统检 测方法相比，此方法对锌( I I )的检测下限 更低，操作更简单，而且它可用于检测复 杂介质中痕量的不稳定锌( I I )。该研究结 果已发表在国际科学期刊Biosensors and Bioelectronics 。 Develop a Novel Biosensor for Labile Zn ( II ) Quantification 開發新型生物傳感器用於不穩定Zn ( II ) 的測量 Prof. Wen-Xiong Wang 王文雄教授 City University of Hong Kong 香港城市大学 Zn2+ directed recession of red pigment in Ade(-) yeast. 锌(II)导致Ade(-) 酵母中的红色素衰退
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