School of SCIENCE 4 life-sci.hkust.edu.hk Division of Life Science Research Foci Facilities The Division is excellently supported for research in a broad range of areas. The Laboratory Animal Facility provides a centralized and modern facility for animal studies. State-of-theart instruments for biochemical and cellular studies are also readily available at the Biosciences Central Research Facility. Facilities in the Division include: Faculty members working in these areas form coordinated research teams. Synergy between research laboratories empowers multi-disciplinary investigation of biological problems. At the same time, it creates a stimulating atmosphere in which students experience the challenge of modern research through in-depth participation. Cellular Regulation and Signalling Cancer Biology Developmental Biology Molecular and Cellular Neuroscience Macromolecular Structure and Function Biotechnology and Medicinal Biochemistry Cell Culture Dedicated suites for the cultivation, maintenance, characterization and cold storage of animal cells, as well as the production of monoclonal antibodies. Molecular and Cellular Biology Major shared equipment includes high speed and ultracentrifuges, spectrophotometers and spectrofluorimeters, scintillation counters, gel imaging systems, lyophilizer, automated plate pourer and stackable shaker-incubators. Biomolecular Nuclear Magnetic Resonance Spectrometer Our state-of-the-art NMR facility consists of 500, 750 and 800 MHz NMR spectrometers equipped with cryoprobes for studies of structures, dynamics and functions of proteins, nucleic acids, and other biomolecules in solution and for drug screening and design. Cryo-EM Facility The Center houses several microscopes for transmission electron microscopy (TEM), including a 300kV Titan Krios G3i equipped with K3, a 200kV Glacios, and a 120kV Talos L120C. Additionally, an Aquilos II cryo-FIB with i-FLM fluorescence microscope, and other supporting instruments are installed to facilitate single-particle cryo-EM and cryo-ET research.
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